At least 46 people have died after two high-speed trains collided in Spain's Toledo province, with preliminary reports pointing to a tragic signaling fault and human error.

At least 46 people died in central Spain when a high-speed train collided with a stationary train due to human error, marking the country's second major rail disaster this year.

At least 46 people are dead and dozens injured after a state-owned Renfe AVE train rear-ended a stationary Iryo train in Spain's Toledo province.

At least 46 people are dead after a high-speed passenger train rear-ended another near Toledo, Spain, with officials pointing to manual signalling errors.